Genotoxicity Assessment of a Natural Anti-cancer Compound Zerumbone in CHO Cell Lines
نویسندگان
چکیده
منابع مشابه
Sceptrin, a Marine Natural Compound, Inhibits Cell Motility in a Variety of Cancer Cell Lines
Sceptrin, a natural compound produced by various marine sponges, was tested for its effect on cell motility. We report for the first time that sceptrin inhibits cell motility in several cancer cell lines. The compound shows no toxicity at concentrations that are double the amount of sceptrin required for maximal inhibitory effect. Both random and factor-induced migration were impaired, suggesti...
متن کاملCytotoxicity and genotoxicity of stilbene derivatives in CHO-K1 and HepG2 cell lines
The cytotoxicity and genotoxicity of the stilbenes (E)-methyl-4-(3-5-dimethoxystyryl)benzoate (ester), (E)-4-(3-5-dimethoxystyryl)aniline (amino), (Z)-1,3-dimethoxy-5-(4-methoxystyryl)benzene (cis-TMS) and (E)-1,3-dimethoxy-5-(4-methoxystyryl)benzene (trans-TMS) were investigated in this work. Structural modifications of resveratrol, a naturally occurring stilbene, have been previously performe...
متن کاملAnti-cancer compound from medicinal mushrooms
Various mushrooms have been used as folk medicine for long times, the higher Basidiomycetes have become a matter of great interest due to their diverse nutritional, medicinal, and pharmacological properties. 650 species and intraspecific taxa from 182 genera of higher Hetero- and Homo-basidiomycetes have been listed that contain biological active anti-tumor and immunostimulative polysaccharides...
متن کاملAnti-cancer compound from medicinal mushrooms
Various mushrooms have been used as folk medicine for long times, the higher Basidiomycetes have become a matter of great interest due to their diverse nutritional, medicinal, and pharmacological properties. 650 species and intraspecific taxa from 182 genera of higher Hetero- and Homo-basidiomycetes have been listed that contain biological active anti-tumor and immunostimulative polysaccharides...
متن کاملExpression of Recombinant Alpha-1 Antitrypsin in CHO and COS-7 Cell Lines Using Lentiviral Vector
In this study, in order to facilitate and accelerate the production of eukaryotic protein alpha 1-antitrypsin (AAT) with correct post-translational modifications, a protein production system based on the transduction of CHO and COS-7 cells using lentiviral vectors was developed. Human AAT cDNA was cloned into a replication-defective lentiviral vector. The transgene AAT-Jred chimer was transferr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Cancer Research
سال: 2012
ISSN: 1811-9727
DOI: 10.3923/ijcr.2012.119.129